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Glycoscience —
Biology's Newest
Unchartered Frontier

by Kathleen Cason

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Sweet Dreams

CCRC Milestones

Part two

Plant cell walls and regulatory carbohydrates

  • Research in this area focuses on the primary cell walls in plants: uncovering the composition of the walls, the structure of the polymers and how they assemble to form cell walls, and the biochemical pathways involved.
  • Complex carbohydrates that regulate plant growth, development and responses either to the physical environment or to other organisms are studied by several research groups at the center.


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New cancer diagnostics, vaccines and therapies

  • Several studies focus on tumor-associated antigens that can be used to develop vaccines or diagnostic tests.
  • Carbohydrate markers in the blood have been identified and used in a diagnostic test for choriocarcinoma — a rare cancer where embryos turn into deadly tumors.
  • New research is under way to find carbohydrate markers to detect breast, prostate and ovarian cancers.
  • Other studies seek to block the cell surface carbohydrates that allow cancer cells to spread.
  • Pectin — a complex carbohydrate from plants — may have a role in prostate cancer prevention. CCRC scientists are examining pectin’s anti-cancer properties in a collaborative project with Medical College of Georgia researchers.
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